Peripheral Dysostosis

Sotos' syndrome (cerebral gigantism) with peripheral dysostosis.

Evans, P. R. (1971). Archives of Disease in Childhood, 46, 199. Sotos' syndrome (cerebral gigantism) with peripheral dysostosis. A girl had short stumpy hands and feet due to osseous dystrophy; in other respects she showed all the main and many of the minor features of Sotos' syndrome during infancy. Then she was on the 97th centile for height, but she grew to be a woman on the 10th centile. Me...

A family with diaphyseal aclasis and peripheral dysostosis.

Autosomal dominant inheritance of a type of peripheral dysostosis occurred in a family with diaphyseal aclasis. The features of their type of peripheral dysostosis were short limbed short stature, normal intelligence, very stubby fingers, flat face and nose, shortened metacarpals and terminal phalanges, thickened beaten-copper skull vault, and advanced skeletal maturation.

Metaphyseal dysostosis.

Metaphysial Dysostosis, Type Schmid.

It is interesting to note the way in which medical knowledge has developed over the years with regard to diseases superficially akin to classical rickets. The first stage followed as a result of the disappearance, owing to the improved knowledge of nutrition, of classical rickets as a common source of bony deformity. This led to the clearer recognition of the remaining 'resistant' forms of rick...

A Case of Craniocleido-Dysostosis

A Muslim boy of 15 years came in September 1946 for a sinus under his chin of 3 years' duration. He had a carious molar tooth in the lower row, which was responsible for the sinus. The sinus was scraped and the tooth removed. This resulted in closure of sinus within a few days. While he was under treatment for the sinus, it was accidentally revealed that he had no fully developed clavicles and ...